陈亨业

出生年月：1990年10月

民族：汉族

职称：副教授/硕士生导师

学科专业：药物分析；化学计量学

研究方向：食药安全的可视化阵列传感分析

电子邮箱：chenhengye@126.com

教育及工作经历:

2024/03-至今 中南民族大学，药学院，副教授

2018/07-2024/03 中南民族大学，药学院，讲师

2016/10 - 2017/10 瑞士日内瓦大学，联合培养博士，导师：François Barja

2012/09 -2018/06 华中农业大学，食品科学技术学院，博士，导师：陈福生教授

2008/09 - 2012/06 华中农业大学，食品科学技术学院，学士

教学工作:

承担和参与多门课程教学，本科生课程：《药学仪器分析（B）》、《药物分析信息学》、《药学仪器分析实验》等；研究生课程：《现代中药分析学》、《中药学及民族药学专论》等。获批校级教研项目1项，参编中药材安全检测和药食两用植物资源相关学术著作6部，发表教研论文1篇；指导多名本科生在本领域权威SCI期刊发表学术论文，并获校级优秀学士学位论文。

社会兼职:

J. Food. Quality客座编辑；中国民族医药学会健康产业分会理事，湖北省生物工程学会会员，湖北省植物学会会员，阿拉山口市金陆工程项目管理有限公司科技创新版块专家顾问。

科研项目:

1.国家自然科学基金委员会，面上项目，热加工食品中结合态晚期糖基化产物的原位识别和动态减控机制研究，202401-202712，50万，主持；

2.国家自然科学基金委员会，青年项目，吡嗪类化合物靶向阵列传感器构建及对高温大曲白酒的精准鉴别，202101-202312，24万，主持；

3.江苏省市场监督管理局，科技计划项目，可视化阵列传感结合化学计量学对浓香型白酒真实性的免仪器鉴别研究，202401-202512，12万，主持；

4.江苏省市场监督管理局，科技计划项目，金属离子介导的可视化阵列传感对浓香型白酒真实性的精准鉴别，202301-202501，12万，主持；

5.中南民族大学引进人才项目，纳米效应多元光谱传感对中国白菊中农残的快速识别机制研究，202204-202503，5万，主持；

6.中央高校基本科研业务费专项资金项目，基于可视化阵列传感器的术类药材特征成分免仪器快检技术研究，202304-202604，5万，主持；

7.国家重点研发计划，食品营养与安全关键技术研发重点专项，课题二子课题：风险因子靶向吸附消减技术研究，202312-202712，95万，参与（骨干）；

8.国家重点研发计划，“中医药现代化”重点专项，课题二：基于土壤特征的道地药材品质形成机制研究，202010-202209，2584万元，参与（骨干）；

9.国家自然科学基金委员会，面上项目，纳米效应阵列纸传感器构建及对蔬菜中内吸性农残精准识别机制研究，202001-202312，58万，参与（骨干）；

10.横向课题，化妆品中重金属Pb检出技术开发，202212-202312，6万，主持；

11.横向课题，植物源食品安全快检及真实性溯源实验装备，202312-202412，35万，参与（排第2）；

12.横向课题，化妆品中原料成分质量控制快检方法，202212-202312，30万，参与（排第2）；

13.横向课题，浓香型白酒产地特征量子点芯片指纹图谱技术研发与集成，201907-202207，50万，参与（排第2）；

14.中南民族大学教研项目，大数据时代下药物分析信息学课程的教学方法改革研究，202206-202406，1万，主持。

代表性论文:

[1]Chen Hengye^#, Ren Lixue^#, Yang Yinan,Long Wanjun, Lan Wei, Yang Jian,Fu Haiyan*. Three-dimensional fluorescence combined with alternating trilinear decomposition and random forest algorithm for the rapid prediction of species, geographical origin and main components of Glycyrrhizae Radix et Rhizoma (Gancao),Food Chemistry,2024,444: 138603.

[2]Lei Guanghua, Guan Yuting Guan, Long Wangjun, Lan Wei, Hu Zikang, Bai Xiuyun, Huang Yun,YangJian Yang,Chen Hengye*, Fu Haiyan*. Prediction of Active Compound Content and Identification of Origin of Chrysanthemi Flos using Fe3+-mediated Multi-Mechanism Fluorescence Visual Sensor with Chemometrics,Sensors and actuators B: chemical,2023, 399: 134793.

[3]Zhu Yanmei^#, Xiang Fushuang^#, Su Yuanyuan, Jiang Xue, Cang Yipeng, Long Wanjun, Lan Wei, Deng Gaoqiong,Chen Hengye *, She Yuanbin*, Fu Haiyan*. Authenticity identification of high-Temperature Daqu Baijiu through multi-channel visual array sensor of organic dyes combined with smart phone App.Food Chemistry,2023,438：137980.

[4]Chen Hengye^#,Zhu Yanmei^#, Xie Yufei, Long Wanjun, Lan wei,She Yuanbin, Fu Haiyan*. Rapid identification of high-temperature Daqu Baijiu with the same aroma type through the excitation emission matrix fluorescence of maillard reaction products.Food Control.2023, 153: 109938.

[5]Deng Gaoqiong #,Chen Hengye#, Shi Qiong, Ren Lixue, Liang Ke, Long Wanjun, Lan Wei, Han Xiaole*, She Yuanbin, Fu Haiyan*. Colorimetric assay based on peroxidase-like activity of dodecyl trimethylammonium bromide-tetramethyl zinc (4-pyridinyl) porphyrin for detection of organophosphorus pesticides.Microchimica Acta,2022, 189(10): 375.

[6]Liu Rui,Chen Hengye, Bai Xiuyun,Huang Yun,Li Huiling, Long Wanjun, Lan Wei,She Yuanbin, Fu Haiyan*. Visual classification for sesame oil adulteration detection and quantification of compounds used as adulterants using flavor compounds targeted array sensor in combination with DD-SIMCA and PLS.Sensors and Actuators B: Chemical.2022, 357: 131335.

[7]Liu Rui^#,Chen Hengye^#,Wang Shuo,Wei Liuna,Yu Yongjie, Lan Wei,Fu Haiyan*, Yang Jian*, Guo Lanping*. Maillard reaction products and Guaiacol as production process and raw material markers for the authenticity identification of sesame oil.Journal of the Science of Food and Agriculture.2022,102:250-258.

[8]WuMeixia,Chen Hengye, Fan Yao, Wang Songtao, Hu Ying, Liu Jian, Shen Caihong, Zhou Chunsong, Fu Haiyan*, She Yuanbin*. Carbonyl flavor compound-targeted colorimetric sensor array based on silver nitrate and o-phenylenediamine derivatives for the discrimination of Chinese Baijiu.Food Chemistry.2022, 372: 131216.

[9]Chen Hengye^#,ShiQiong^#,Deng gaoqiong, Chen Xiahe, Yang Yunfang, Lan Wei,Hu Ying,Zhang Lei, Xu Lu, Li Chunyuan, Zhou Chunsong,She Yuanbin, Fu Haiyan*. Rapid and highly sensitive colorimetric biosensor for the detection of glucose and hydrogen peroxide based on nanoporphyrin combined with bromine as a peroxidase-like catalyst.Sensors and Actuators B: Chemical.2021, 343: 130104.

[10]Chen Hengye^#, Zhang Lei^#, Hu Ying,Zhou Chunsong,Lan Wei, Fu Haiyan*, She Yuanbin*. Nanomaterials as optical sensors for application in rapid detection of food contaminants, quality and authenticity.Sensors and Actuators B: Chemical.2021, 329: 129135.

[11]WangShou^#,Chen Hengye^#,Xie Hongliang, Wei Liuna, Xu Lu, Zhang Lei, Lan Wei,Zhou Chunsong, She Yuanbin, Fu Haiyan*. A novel thioctic acid-carbon dots fluorescence sensor for the detection of Hg2+ and thiophanate methyl via S-Hg affinity.Food Chemistry.2021, 346: 128923.

[12]Chen Hengye^#,LiuRui^#,Guo Xiaoming, Deng Gaoqiong, Xu Lu, Zhang Lei, Lan Wei,Zhou Chunsong, She Yuanbin, Fu Haiyan*. Visual paper-based sensor for the highly sensitive detection of caffeine in food and biological matrix based on CdTe-nano ZnTPyP combined with chemometrics.Microchimica Acta.2021,188: 27.

[13]Chen Hengye^#, Wei Liuna^#, Guo Xiaoming, Hai Chengying, Xu Lu, Zhang Lei, Lan Wei,Zhou Chunsong,She Yuanbin,Fu Haiyan*. Determination of L-theanine in tea water using fluorescence-visualized paper-based sensors based on CdTe quantum dots/corn carbon dots and nano-porphyrinwithchemometrics.Journal of the Science of Food and Agriculture.2021,101: 2552-2560.

[14]Wei Liuna#,Chen Hengye#, Liu Rui, Wang Shuo, Liu Tingkai, Hu Zikang, Lan Wei, Yu Yongjie*, She Yuanbin, Fu Haiyan*. Fluorescent sensor based on quantum dots and nano porphyrin for highly sensitive and specific recognition of ethyl carbamate in fermented food.Journal of the Science of Food and Agriculture,2021, 101:6193.

[15]Chen Hengye^#, Hu Ou^#, Fan Yao, Xu Lu, Zhang Lei, Lan Wei, Hu Ying, Xie Xingrui, Ma Lixia, She Yuanbin, Fu Haiyan*. Fluorescence paper-based sensor for visual detection of carbamate pesticides in food based on CdTe quantum dot and nano ZnTPyP.Food Chemistry.2020,327:127075.

[16]Chen Hengye^#, Shi Qiong^#, Fu Haiyan*, Hu Ou, Fan Yao, Xu Lu, Zhang Lei, Lan Wei, Sun Donglei, Yang Tianming, She Yuanbin *. Rapid detection of five pesticide residues using complexes of gold nanoparticle and porphyrin combined with ultraviolet visible spectrum.Journal of the Science of Food and Agriculture.2020, 100(12): 4464-4473.

[17]Chen Hengye^#, Wang Shuo^#, Fu Haiyan*, Chen Fusheng, Zhang Lei, Lan Wei, Yang Jian, Yang Xiaolong, She Yuanbin. A colorimetric sensor array for recognition of 32 Chinese traditional cereal vinegars based on “turn-off/on” fluorescence of acid-sensitive quantum dots.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2020, 227: 117683.

[18]Chen Hengye^#, Wang Shuo^#, Fu Haiyan*, Xie Hongliang, Lan Wei, Xu Lu, Zhang Lei, She Yuanbin*. Dual-QDs ratiosfluorescent probe for sensitive and selective detection of silver ions contamination in real sample.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2020, 234: 118248.

[19]Chen Hengye^#,Hu Ou^#, Fu Haiyan*,Fan Yao, Xu Lu,Meng Qingjun,Zhang Lei, Lan Wei,Wu Chunying, Tang Siyi,She Yuanbin*. Paper-based sensor for visual detection of Ag+based on a “turn-off-on” fluorescent design.Microchemical Journal,2020:157:104887.

[20]Chen Hengye,Chen Tao,Giudici Paolo,Chen Fusheng*.Vinegar Functionson Health:Constituents,Sources,and　Formation Mechanisms.Comprehensive Reviewsin Food Science and Food Safety,2016,15(6):1124-1138.

代表性专利:

[1]陈亨业，朱艳美，付海燕，佘远斌，龙婉君，兰薇．一种基于美拉德反应产物荧光信号解析的高温大曲白酒鉴别和化合物预测方法．中国发明专利，ZL 202310400903.8（已授权）．

[2]付海燕，陈亨业，王硕，佘远斌．一种基于量子点荧光猝灭的仿生阵列传感器及其应用．中国发明专利，ZL 201910095806.6（已授权）．

[3]陈福生，陈亨业．一株高产苯乳酸的葡糖醋杆菌及其苯乳酸的制备方法．中国发明专利，Z L201610853578.0（已授权）．

[4]付海燕，韦柳娜，陈亨业，兰薇，佘远斌．一种用于淀粉类掺假判别的碳量子点荧光传感方法．中国发明专利．ZL 202010483828.2（已授权）．

[5]付海燕，韦柳娜，陈亨业，时琼，兰薇，佘远斌．一种邻苯二甲酸二（2-乙基己基）酯的快速比色检测法．中国发明专利．ZL 202010443474.9（已授权）．

[6]付海燕,刘瑞,陈亨业,兰薇,佘远斌.一种快速检测食品中白藜芦醇的方法.中国发明专利．ZL202010618266.8（已授权）.

[7]付海燕，刘瑞，陈亨业，兰薇，佘远斌.一种快速定量测定pH值和/或尿酸的方法.中国发明专利，专利号：ZL 202010862685.6（已授权）.

[8]付海燕，邓高琼，韦柳娜，王硕，陈亨业，佘远斌，周春松.基于纳米金蚀刻检测农药甲萘威的方法.中国发明专利,专利号：ZL 202110440927.7（已授权）

[9]付海燕，王硕，陈亨业，邓高琼，刘庭恺，兰薇，佘远斌.一种快速检测汞离子或甲基硫菌灵的方法.中国发明专利，专利号：ZL 202011478158.1（已授权）

[10]付海燕，韦柳娜，陈亨业，邓高琼，兰薇，佘远斌.一种圆片状四-（4-苯基）钡纳米卟啉荧光探针及利用其检测杀螟丹的方法.中国发明专利，专利号：ZL 202011479881.1（已授权）.

[11]付海燕，刘瑞，陈亨业，杨健，王游游，周春松，佘远斌.一种检测芝麻油掺假的方法.中国发明专利专利号：ZL 202110760920.3（已授权）.

[12]付海燕，王硕，时琼，陈亨业，兰薇，佘远斌.一种基于碳点-量子点比率荧光传感器的制备方法及其应用.中国发明专利，专利号：ZL 202010358457.5（已授权）.

[13]付海燕，韦柳娜，陈亨业，佘远斌.一种用于实时检测水环境中有害物质的装置.中国实用新型专利，申请号：202021712240.1,专利号：ZL 202021712240.1（已授权）..

[14]付海燕，韦柳娜，陈亨业，王硕，周春松，佘远斌.一种比色检测装置.中国实用新型专利，申请号：202120325824.1,申请日：2021-02-04,专利号：ZL202120325824.1（已授权）.

[15]Haiyan Fu, Jian Yang, Xiaolong Yang, Yuanbin She,Hengye Chen, Wanjun Long, Shuo Wang,Xueqing Zeng, Xiuyun Bai, Methodfor Identifying Originof Chrysanthemi Flos. US 11567009 B1，2023-01-31（已授权，美国发明专利）

代表性软著:

[1]陈亨业，付海燕，佘远斌，朱艳美，龙婉君，兰薇.白酒可视化传感鉴别微信小程序.软件著作，登记号：2023SR1480679，2023-11-21.

[2]付海燕，陈亨业，杨健，龙婉君，兰薇.不同产地和品种中国白菊农药残留查询系统.软件著作，登记号：2022SR1535963，2022-11-18.

[3]付海燕，杨健，陈亨业，龙婉君，杨小龙，兰薇.百合品质的荧光可视化表征软件V1.0.软件著作，登记号：2022SR1535808，2022-11-18.

[4]付海燕，杨健，龙婉君，杨小龙，陈亨业.百合纳米效应红外光谱表征软件.软件著作，登记号：2022SR0186341，2021-12-01.

[5]付海燕，杨健，陈亨业，龙婉君，杨小龙.百合品质形成及其成分因子协同贡献查询系统.软件著作，登记号：2022SR0186339，2021-12-01.

[6]付海燕，杨健，杨小龙，陈亨业，兰薇.白菊品质可视化传感比色表征软件.软件著作，登记号：2021SR1348957，2021-07-12.

[7]付海燕，杨健，杨小龙，陈亨业，兰薇.菊花特征品质因子与土壤矿质元素关联性分析系统.软件著作，登记号：2021SR1348932，2021-07-12.

代表性专著

[1]陈亨业（参编）.民族植物资源化学与生物活性研究.北京:化学工业出版社, 2022.06.

[2]陈亨业（参编）.醋酸菌研究与应用.北京:化学工业出版社, 2022.04.

[3]陈亨业（参编）.中药材重金属研究及国际标准制定.北京:中国中药出版社, 2023.07.

[4]陈亨业（参编）.中药材农药残留研究及国际标准制定.北京:中国中药出版社, 2023.08.

[5]陈亨业（参编）.中药材二氧化硫研究及国际标准制定.北京:中国中药出版社, 2023.09.

[6]陈亨业（参编）.武陵山区药用及食用植物资源-湖北册.化学工业出版社, 2023.11.